The Longevity Study

Participation

The Longevity Study has received approval from the Institutional Review Board (IRB) of Mass General Brigham, the largest hospital system at Harvard Medical School, under the ID #2024P002140. This study will assess the population’s molecular variation and dynamics, with a specific focus on biological age.

We are now seeking the first 100 volunteers. Sample and data collection will take place between October 31st and November 2nd and coincide with the 2024 Biomarkers of Aging Consortium Conference. Participation is entirely voluntary.

Who can take part?

Generally healthy individuals aged 18 and older weighing more than 110 lb (49.8 kg) can take part in this study. Participants should also:

• Be free of cold and flu symptoms on the day of collection
• Have had no infections within two weeks prior to collection
• Have no symptoms of heart conditions within six months prior to collection
• Have no known sickle cell disease or anemia
• Not have donated more than 550 ml of blood during the preceding eight weeks (and no more than one blood draw during the preceding week)

What will the study involve?

🩸 Participation involves a single blood draw of a maximum of 50 ml (approximately 3 tablespoons) of blood.

📋 Additionally, participants will be asked to fill in a questionnaire that allows us to check their health status and complete a set of simple non-invasive tests to assess functional and cognitive performance.

Our approved protocol, consent, questionnaires and tests are available below:

• Protocol
• Consent
• Longevity Questionnaire
• Functional Tests

The total effort for participation should be no more than 30 minutes.

What will my samples and data be used for?

Your blood samples will be used to study the following molecular features:

• Epigenomics: Understanding how your genes are regulated.
• Transcriptomics: Examining gene expression levels.
• Proteomics: Detailing the proteins in your sample.
• Metabolomics: Exploring how your body processes food into energy.

All your samples and data will be securely stored.

What are the risks and benefits of participation?

You will receive a $50 gift certificate, as well as complimentary virtual access to stream the Biomarkers of Aging Conference for this year, upon completion of your participation. In addition, your participation may contribute new insights to the field of aging research and longevity.

The main risks of being in the study are related to blood collection. We anticipate these risks to be minimal, but you may experience side effects such as slight pain, bruising, or local infection at the site.

Participating in this study will not affect your medical care.

All information is also found in our approved Informed Consent sheet, which you can download here.

Registering Interest

If you are interested in learning more about the study and potential participation, please register your interest below, and we will be in touch with more information.